Gonyautoxin-5

• CAT Number: T000014
• CAS Number: 64296-25-9
• Molecular Formula: C10 H17 N7 O7 S
• Molecular Weight: 379.35
• Purity: ≥95%
• Storage: 2-8°C
• IUPAC Name: [(3aS,4R,10aS)-2,6-diamino-10,10-dihydroxy-3a,4,8,9-tetrahydro-1H-pyrrolo[1,2-c]purin-4-yl]methoxycarbonylsulfamic acid
• InChI: InChI=1S/C10H17N7O7S/c11-6-14-5-4(3-24-8(18)16-25(21,22)23)13-7(12)17-2-1-9(19,20)10(5,17)15-6/h4-5,19-20H,1-3H2,(H2,12,13)(H,16,18)(H3,11,14,15)(H,21,22,23)/t4-,5-,10-/m0/s1
• InChIKey: JKKCSFJSULZNDN-HGRQIUPRSA-N
• SMILES: C1CN2C(=NC(C3C2(C1(O)O)NC(=N3)N)COC(=O)NS(=O)(=O)O)N

Gonyautoxin-5 (CAS 64296-25-9) is one of the derivatives of Gonyautoxins (GTX), a few similar toxic molecules that are naturally produced by algae. GTXs are part of the group of saxitoxins, a large group of neurotoxins. 

Reference

1: Selwood AI, Waugh C, Harwood DT, Rhodes LL, Reeve J, Sim J, Munday R. Acute Toxicities of the Saxitoxin Congeners Gonyautoxin 5, Gonyautoxin 6, Decarbamoyl Gonyautoxin 2&3, Decarbamoyl Neosaxitoxin, C-1&2 and C-3&4 to Mice by Various Routes of Administration. Toxins (Basel). 2017 Feb 21;9(2). pii: E73. doi: 10.3390/toxins9020073. PubMed PMID: 28230783; PubMed Central PMCID: PMC5331452.
2: Watanabe R, Suzuki T, Oshima Y. Development of quantitative NMR method with internal standard for the standard solutions of paralytic shellfish toxins and characterisation of gonyautoxin-5 and gonyautoxin-6. Toxicon. 2010 Sep 15;56(4):589-95. doi: 10.1016/j.toxicon.2010.06.002. Epub 2010 Jun 9. PubMed PMID: 20538011.