For research use only. Not for therapeutic Use.
Golgicide A-2 (GCA-2), a Golgicide A (GCA) derivative, is the most active enantiomer of GCA. Golgicide A-2 displays high selectivity and efficiency in killing An. stephensi larvae and can be used for the research of dengue virus related diseases[1].
GCA-2 is effective in killing both Ae. Aegypti and An. Stephensi larvae, while it is displays distinct and strongly selective cytotoxicity towards Ae. Stephensi larvae with a mortality of 83.4%[1].
| CAS Number | 1394285-50-7 |
| Synonyms | (3aS,4R,9bR)-6,8-difluoro-4-pyridin-3-yl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline |
| Molecular Formula | C17H14F2N2 |
| Purity | ≥95% |
| InChI | InChI=1S/C17H14F2N2/c18-11-7-14-12-4-1-5-13(12)16(10-3-2-6-20-9-10)21-17(14)15(19)8-11/h1-4,6-9,12-13,16,21H,5H2/t12-,13+,16+/m1/s1 |
| InChIKey | NJZHEQOUHLZCOX-WWGRRREGSA-N |
| SMILES | C1C=CC2C1C(NC3=C2C=C(C=C3F)F)C4=CN=CC=C4 |
| Reference | [1]. Daniel J Mack, et al. Distinct biological effects of golgicide a derivatives on larval and adult mosquitoes. Bioorg Med Chem Lett |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
