CONTACT US
Home > Inhibitors/Agonists>LRRK2> > GNE-7915
GNE-7915

GNE-7915

  • CAT Number: I001355
  • CAS Number: 1351761-44-8
  • Molecular Formula: C₁₉H₂₁F₄N₅O₃
  • Molecular Weight: 443.4
  • Purity: ≥95%
Inquiry Now

GNE-7915 (Cat.No:I001355) is a small molecule compound under investigation for its potential therapeutic applications. It is an inhibitor of the enzyme sialic acid synthase (SAS), which is involved in cellular metabolism. GNE-7915 has shown promise in preclinical studies for its potential in treating certain types of cancer and autoimmune disorders. 

Catalog Number I001355
CAS Number 1351761-44-8
Molecular Formula

C₁₉H₂₁F₄N₅O₃

Purity 95%
Target LRRK2
Solubility DMSO: ≤ 14.33 mg/mL
Storage Store at -20°C
IC50 9 nM (cellular assay)
IUPAC Name [4-[[4-(ethylamino)-5-(trifluoromethyl)pyrimidin-2-yl]amino]-2-fluoro-5-methoxyphenyl]-morpholin-4-ylmethanone
InChI 1S/C19H21F4N5O3/c1-3-24-16-12(19(21,22)23)10-25-18(27-16)26-14-9-13(20)11(8-15(14)30-2)17(29)28-4-6-31-7-5-28/h8-10H,3-7H2,1-2H3,(H2,24,25,26,27)
InChIKey XCFLWTZSJYBCPF-UHFFFAOYSA-N
SMILES CCNC1=NC(=NC=C1C(F)(F)F)NC2=C(C=C(C(=C2)F)C(=O)N3CCOCC3)OC
Reference

<p>
[1]. Estrada AA, et al. Discovery of highly potent, selective, and brain-penetrable leucine-rich repeat kinase 2 (LRRK2) small molecule inhibitors. J Med Chem. 2012 Nov 26;55(22):9416-33.
</p>

Request a Quote

Contact Us at MuseChem

We are committed to providing you with reliable, cost-effective solutions for your chemical needs, while ensuring your safety and comfort. Our team of experts is always available to answer your questions and help you navigate the complexities of the chemical industry.

Whether you're looking for a specific product or need help with a custom synthesis project, we're here to help you discover a new world of chemical possibilities. Contact us today to learn more about how we can assist you with all of your chemical needs.

Our goal is to make the process of ordering chemicals as seamless and hassle-free as possible. Let us know how we can assist you, and we'll get back to you as soon as possible. We look forward to hearing from you!