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GlyT2-IN-1

GlyT2-IN-1

  • CAT Number: I003585
  • CAS Number: 448947-81-7
  • Molecular Formula: C13H8Cl2N4S2
  • Molecular Weight: 355.3
  • Purity: ≥95%
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GlyT2-IN-1(CAT: I003585) is a compound that acts as an inhibitor of glycine transporter 2 (GLYT2). GlyT2 is responsible for the reuptake of glycine from the synapse, playing a crucial role in regulating glycine levels and synaptic transmission. By inhibiting GLYT2, GlyT2-IN-1 can increase glycine concentrations in the synaptic cleft, leading to enhanced glycine neurotransmission. This compound has been studied for its potential therapeutic applications in neurological and psychiatric disorders, such as schizophrenia and neuropathic pain, where modulating glycine transmission may have beneficial effects.

Catalog Number I003585
CAS Number 448947-81-7
Molecular Formula

C13H8Cl2N4S2

Purity 95%
Target GLYT2
Solubility DMSO: ≥ 34 mg/mL
Storage 4°C
InChIKey BQNXBSYSQXSXPT-UHFFFAOYSA-N
Reference

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<br>[1]. Rousseau F, et al. The glycine transporter GlyT2 controls the dynamics of synaptic vesicle refilling in inhibitory spinal cord neurons. J Neurosci. 2008 Sep 24;28(39):9755-9768.
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