Glycocholic acid

• CAT Number: R046252
• CAS Number: 475-31-0
• Molecular Formula: C26H43NO6
• Molecular Weight: 465.62
• Purity: ≥95%
• Synonyms: 2-[[(4R)-4-[(3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]acetic acid
• InChI: InChI=1S/C26H43NO6/c1-14(4-7-22(31)27-13-23(32)33)17-5-6-18-24-19(12-21(30)26(17,18)3)25(2)9-8-16(28)10-15(25)11-20(24)29/h14-21,24,28-30H,4-13H2,1-3H3,(H,27,31)(H,32,33)/t14-,15+,16-,17-,18+,19+,20-,21+,24+,25+,26-/m1/s1
• InChIKey: RFDAIACWWDREDC-FRVQLJSFSA-N
• SMILES: C[C@H](CCC(=O)NCC(=O)O)[C@H]1CC[C@@H]2[C@@]1([C@H](C[C@H]3[C@H]2[C@@H](C[C@H]4[C@@]3(CC[C@H](C4)O)C)O)O)C

Glycocholic acid（Cat No.:R046252）is a bile acid conjugate with the molecular formula C26H43NO6, formed by the amidation of cholic acid with glycine. It is a naturally occurring component of bile, playing a crucial role in the emulsification and absorption of dietary fats and fat-soluble vitamins in the small intestine. Glycocholic acid is amphipathic, allowing it to act as a biological detergent. In research and pharmaceutical applications, it is used to study lipid metabolism, bile acid transport, and liver function. It is typically supplied as a sodium salt and handled under standard lab conditions.

Reference

[1]. Lo YL, et al. Inhibit multidrug resistance and induce apoptosis by using glycocholic acid and epirubicin. Eur J Pharm Sci. 2008 Sep 2;35(1-2):52-67.
[Content Brief]