For research use only. Not for therapeutic Use.
Glycocholic acid-d₅（Cat No.:I044971）is a deuterium-labeled analog of glycocholic acid, a primary bile acid conjugated with glycine. It is used as an internal standard in mass spectrometry for accurate quantification of bile acids in biological samples. The d₅ isotopic labeling enables precise tracing in metabolic studies involving bile acid synthesis, enterohepatic circulation, and liver-gut axis regulation. Glycocholic acid-d₅ is valuable in research on liver function, lipid digestion, and diseases such as cholestasis or non-alcoholic fatty liver disease (NAFLD).
| CAS Number | 2170091-95-7 |
| Synonyms | 2-[[(4R)-4-[(3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-2,2,3,4,4-pentadeuterio-3,7,12-trihydroxy-10,13-dimethyl-1,5,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl]pentanoyl]amino]acetic acid |
| Molecular Formula | C26H38D5NO6 |
| Purity | ≥95% |
| IUPAC Name | 2-[[(4R)-4-[(3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-2,2,3,4,4-pentadeuterio-3,7,12-trihydroxy-10,13-dimethyl-1,5,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl]pentanoyl]amino]acetic acid |
| InChI | InChI=1S/C26H43NO6/c1-14(4-7-22(31)27-13-23(32)33)17-5-6-18-24-19(12-21(30)26(17,18)3)25(2)9-8-16(28)10-15(25)11-20(24)29/h14-21,24,28-30H,4-13H2,1-3H3,(H,27,31)(H,32,33)/t14-,15+,16-,17-,18+,19+,20-,21+,24+,25+,26-/m1/s1/i8D2,10D2,16D |
| InChIKey | RFDAIACWWDREDC-IYHMEHENSA-N |
| SMILES | [2H][C@]1(C(C[C@@]2([C@H]3C[C@@H]([C@]4([C@H]([C@@H]3[C@@H](C[C@@H]2C1([2H])[2H])O)CC[C@@H]4[C@H](C)CCC(=O)NCC(=O)O)C)O)C)([2H])[2H])O |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
