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GLP-26

GLP-26

  • CAT Number: I018128
  • CAS Number: 2133017-36-2
  • Molecular Formula: C₁₉H₁₇F₂N₃O₃
  • Molecular Weight: 373.35
  • Purity: ≥95%
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GLP-26 is a HBV capsid assembly modulators (CAM), inhibits HBV DNA replication in Hep AD38 system (IC50=3 nM), and reduces cccDNA by >90% at 1 μM.
GLP-26 disrupts the encapsidation of pre-genomic RNA, causes nucleocapsid disassembly and reduces cccDNA pools[1].<br>GLP-26 (0.7-1.7 μM; 3 days) reduces secreted HBeAg in HepNTCP-DL cells transfected with HBV
wild type, with EC50 values of 0.7 μM[2].

Catalog Number I018128
CAS Number 2133017-36-2
Molecular Formula

C₁₉H₁₇F₂N₃O₃

Purity 95%
Reference

[1]. Nijampatnam B, et al. Recent advances in the development of HBV capsid assembly modulators. Curr Opin Chem Biol. 2019 Jun;50:73-79.

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