Ganciclovir sodium

• CAT Number: M001234
• CAS Number: 107910-75-8
• Molecular Formula: C9H12N5NaO4
• Molecular Weight: 277.216
• Purity: ≥95%
• Storage: Store at -20°C
• IUPAC Name: sodium;2-amino-9-(1,3-dihydroxypropan-2-yloxymethyl)purin-6-olate
• InChI: InChI=1S/C9H13N5O4.Na/c10-9-12-7-6(8(17)13-9)11-3-14(7)4-18-5(1-15)2-16;/h3,5,15-16H,1-2,4H2,(H3,10,12,13,17);/q;+1/p-1
• InChIKey: JJICLMJFIKGAAU-UHFFFAOYSA-M
• SMILES: C1=NC2=C(N1COC(CO)CO)N=C(N=C2[O-])N.[Na+]

Ganciclovir Sodium is an acyclovir analog that is a potent inhibitor of the Herpesvirus family including cytomegalovirus. Ganciclovir is used to treat complications from AIDS-associated cytomegalovirus infections.

Reference

1:Stability of ganciclovir sodium in an infusion-pump syringe. Mulye NV, Turco SJ, Speaker TJ.Am J Hosp Pharm. 1994 May 15;51(10):1348-9. No abstract available. PMID: 8085576 2:Stability of ganciclovir sodium and amino acids in parenteral nutrient solutions. Johnson CE, Jacobson PA, Chan E.Am J Hosp Pharm. 1994 Feb 15;51(4):503-8. PMID: 8017417 3:[Stability of dilute solutions of ganciclovir sodium (Cymevan) in polypropylene syringes and PVC perfusion bags]. Phaypradith S, Vigneron J, Perrin A, Durney-Archeray MJ, Hoffman MA, Hoffman M.J Pharm Belg. 1992 Nov-Dec;47(6):494-8. French. PMID: 1289490 4:Stability of ganciclovir sodium in 5% dextrose injection and in 0.9% sodium chloride injection over 35 days. Parasrampuria J, Li LC, Stelmach AH, Sykes TR, Gordon GA.Am J Hosp Pharm. 1992 Jan;49(1):116-8. PMID: 1570851 5:Stability and compatibility of ganciclovir sodium in 5% dextrose injection over 35 days. Silvestri AP, Mitrano FP, Baptista RJ, Williams DA.Am J Hosp Pharm. 1991 Dec;48(12):2641-3. PMID: 1814209 6:Visual compatibility of ganciclovir sodium and total parenteral nutrient solution during simulated Y-site injection. Outman WR, Mitrano FP, Baptista RJ.Am J Hosp Pharm. 1991 Jul;48(7):1538-9. No abstract available. PMID: 1909095 7:Stability of ganciclovir sodium (DHPG sodium) in 5% dextrose or 0.9% sodium chloride injections. Visor GC, Lin LH, Jackson SE, Winterle JS, Lee G, Kenley RA.Am J Hosp Pharm. 1986 Nov;43(11):2810-2. PMID: 3492139