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Gamabufotalin

Gamabufotalin

  • CAT Number: I003612
  • CAS Number: 465-11-2
  • Molecular Formula: C24H34O5
  • Molecular Weight: 402.52
  • Purity: ≥95%
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Gamabufotalin(CAT: I003612)is a prominent bufadienolide compound found in Chansu, a traditional Chinese medicine. It has gained attention for its potential use in cancer therapy due to its favorable metabolic stability and fewer adverse effects compared to other bufadienolides. Gamabufotalin exhibits various biological activities, including anticancer properties. It has been studied for its ability to induce apoptosis (programmed cell death) and inhibit cancer cell proliferation.

Catalog Number I003612
CAS Number 465-11-2
Molecular Formula

C24H34O5

Purity 95%
Solubility 10 mM in DMSO
Storage Store at -20°C
Reference

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<br>[1]. Yu Z, et al. Gamabufotalin, a bufadienolide compound from toad venom, suppresses COX-2 expression through targeting IKKβ/NF-κB signaling pathway in lung cancer cells. Mol Cancer. 2014 Aug 31;13:203.

<br>[2]. Dong Y, et al. Bufadienolide compounds sensitize human breast cancer cells to TRAIL-induced apoptosis via inhibition of STAT3/Mcl-1 pathway. Apoptosis. 2011 Apr;16(4):394-403.

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