Gadoteric Acid

  • CAT Number: M009883
  • CAS Number: 72573-82-1
  • Molecular Formula: C16H25GdN4O8
  • Molecular Weight: 558.65
  • Purity: ≥95%
Inquiry Now

Gadoteric acid (gadoterate meglumine, trade names Artirem, Dotarem) is a macrocycle-structured gadolinium-based MRI contrast agent (GBCA). It consists of the organic acid DOTA as a chelating agent, and gadolinium (Gd3+), and is used in form of the meglumine salt (Gadoterate meglumine).

Catalog Number M009883
CAS Number 72573-82-1
Molecular Formula

C16H25GdN4O8

Purity 95%
Storage Store at RT
InChI 1S/C16H28N4O8.Gd/c21-13(22)9-17-1-2-18(10-14(23)24)5-6-20(12-16(27)28)8-7-19(4-3-17)11-15(25)26;/h1-12H2,(H,21,22)(H,23,24)(H,25,26)(H,27,28);/q;+3/p-3
InChIKey GFSTXYOTEVLASN-UHFFFAOYSA-K
SMILES C1CN(CCN(CCN(CCN1CC(=O)O)CC(=O)[O-])CC(=O)[O-])CC(=O)[O-].[Gd+3]
Reference

1: Gheuens E, Daelemans R, Mesens S. Dialysability of gadoteric acid in patients
with end-stage renal disease undergoing hemodialysis. Invest Radiol. 2014
Aug;49(8):505-8. doi: 10.1097/RLI.0000000000000045. PubMed PMID: 24619209.
<br>

2: Renz DM, Durmus T, B&#246;ttcher J, Taupitz M, Diekmann F, Huppertz A, Pfeil A,
Maurer MH, Streitparth F, Bick U, Hamm B, Fallenberg EM. Comparison of gadoteric
acid and gadobutrol for detection as well as morphologic and dynamic
characterization of lesions on breast dynamic contrast-enhanced magnetic
resonance imaging. Invest Radiol. 2014 Jul;49(7):474-84. doi:
10.1097/RLI.0000000000000039. PubMed PMID: 24637587.

<br>
3: Balassy C, Roberts D, Miller SF. Safety and efficacy of gadoteric acid in
pediatric magnetic resonance imaging: overview of clinical trials and
post-marketing studies. Pediatr Radiol. 2015 Nov;45(12):1831-41. doi:
10.1007/s00247-015-3394-9. Epub 2015 Jun 5. Review. PubMed PMID: 26045036.

<br>
4: Budjan J, Ong M, Riffel P, Morelli JN, Michaely HJ, Schoenberg SO, Haneder S.
CAIPIRINHA-Dixon-TWIST (CDT)-volume-interpolated breath-hold examination (VIBE)
for dynamic liver imaging: comparison of gadoterate meglumine, gadobutrol and
gadoxetic acid. Eur J Radiol. 2014 Nov;83(11):2007-12. doi:
10.1016/j.ejrad.2014.08.003. Epub 2014 Aug 17. PubMed PMID: 25172427.

<br>
5: Maurer M, Heine O, Wolf M, Durmus T, Wagner M, Hamm B. Tolerability and
diagnostic value of gadoteric acid in the general population and in patients with
risk factors: results in more than 84,000 patients. Eur J Radiol. 2012
May;81(5):885-90. doi: 10.1016/j.ejrad.2011.04.022. Epub 2011 May 8. PubMed PMID:
21555197.

<br>
6: Seithe T, Braun J, Wolf M, Vahldiek J, Wolny D, Auer J, Pociej J, Heine O,
Hamm B, de Bucourt M. Diagnostic efficacy and safety of gadoteric acid MR
mammography in 1537 patients. Eur J Radiol. 2016 Dec;85(12):2281-2287. doi:
10.1016/j.ejrad.2016.10.013. Epub 2016 Oct 14. PubMed PMID: 27842678.
<br>

7: Apodaca-Torrez FR, Goldenberg A, Lobo EJ, Farah JF, Trivi&#241;o T, Montero EF,
Schraibman V, Benvenuto RB, Artigiani Neto R. Evaluation of the effects of
noniodinized and iodinized ionic contrast media and gadoteric acid in acute
necrotizing pancreatitis: experimental study in rabbits. Pancreas. 2007
Nov;35(4):e41-4. PubMed PMID: 18090230.

Request a Quote

Contact Us at MuseChem

We are committed to providing you with reliable, cost-effective solutions for your chemical needs, while ensuring your safety and comfort. Our team of experts is always available to answer your questions and help you navigate the complexities of the chemical industry.

Whether you're looking for a specific product or need help with a custom synthesis project, we're here to help you discover a new world of chemical possibilities. Contact us today to learn more about how we can assist you with all of your chemical needs.

Our goal is to make the process of ordering chemicals as seamless and hassle-free as possible. Let us know how we can assist you, and we'll get back to you as soon as possible. We look forward to hearing from you!