Fumonisin B1

• CAT Number: R049027
• CAS Number: 116355-83-0
• Molecular Formula: C34H59NO15
• Molecular Weight: 721.8
• Purity: ≥95%
• Target: Protein Ser/Thr Phosphatases
• Solubility: Limited solubility
• Storage: Store at 4°C
• InChIKey: UVBUBMSSQKOIBE-CPRNOWDYSA-N
• SMILES: C[C@H](N)[C@@H](O)C[C@H](O)CCCC[C@@H](O)C[C@H](C)C[C@H](OC(C[C@H](C(O)=O)CC(O)=O)=O)[C@H](OC(C[C@H](C(O)=O)CC(O)=O)=O)[C@H](C)CCCC

Fumonisin B1(cas 116355-83-0) is a mycotoxin produced from F. moniliforme, a prevalent fungus of corn and other grains. Outbreaks of food poisoning in livestock and humans following the consumption of Fusarium infested corn are caused by fumonisins.

Reference

Structure elucidation of the fumonisins, mycotoxins from Fusarium moniliforme. Bezuidenhout S. C. et al. J. Chem. Soc. Chem. Commun. 1988, 743.

Inhibition of sphingolipid biosynthesis by fumonisins. Implications for diseases associated with Fusarium moniliforme. Wang E. et al. J. Biol. Chem. 1991, 266, 14486.

Inhibition of sphingolipid synthesis affects axonal outgrowth in cultured hippocampal neurons. Harel R. & Futerman A. H. J. Biol. Chem. 1993, 268, 14476.

Fumonisin B1 inhibits sphingosine (sphinganine) N-acyltransferase and de novo sphingolipid biosynthesis in cultured neurons in situ. Merrill A. H. et al. J. Biol. Chem. 1993, 268, 27299.