FR-193879

• CAT Number: I006878
• CAS Number: 194928-82-0
• Molecular Formula: C20H18N4O5S3
• Molecular Weight: 490.567
• Purity: ≥95%
• Synonyms: FR-193879; FR193879; FR 193879.;5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 3-((4-(2-amino-2-oxoethyl)-2-thiazolyl)thio)-8-oxo-7-((2-phenylacetyl)amino)-, (6R,7R)-
• Solubility: Soluble in DMSO
• Storage: 0 - 4°C for short term or -20 °C for long term
• IUPAC Name: (6R,7R)-3-[[4-(2-amino-2-oxoethyl)-1,3-thiazol-2-yl]sulfanyl]-8-oxo-7-[(2-phenylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• InChI: InChI=1S/C20H18N4O5S3/c21-13(25)7-11-8-31-20(22-11)32-12-9-30-18-15(17(27)24(18)16(12)19(28)29)23-14(26)6-10-4-2-1-3-5-10/h1-5,8,15,18H,6-7,9H2,(H2,21,25)(H,23,26)(H,28,29)/t15-,18-/m1/s1
• InChIKey: YINUFDSCPLNLPS-CRAIPNDOSA-N
• SMILES: C1C(=C(N2C(S1)C(C2=O)NC(=O)CC3=CC=CC=C3)C(=O)O)SC4=NC(=CS4)CC(=O)N

FR-193879 is a novel, efficacious cephem derivative with extremely potent therapeutic efficacy against H. pylori.

Reference

1:Yoshida Y, Matsuda K, Sasaki H, Matsumoto Y, Matsumoto S, Tawara S, Takasugi H. Studies on anti-Helicobacter pylori agents. Part 3: A novel, efficacious cephem derivative, FR193879. Bioorg Med Chem Lett. 2004 May 17;14(10):2627-31. PubMed PMID: 15109666.