For research use only. Not for therapeutic Use.
Foxy-5 TFA（Cat No.:I046149）is a synthetic hexapeptide designed as a functional mimetic of Wnt5a, a non-canonical Wnt ligand involved in cell polarity, migration, and signaling. Unlike full-length Wnt proteins, Foxy-5 offers improved stability and solubility while selectively activating Wnt5a-related pathways without driving uncontrolled proliferation. The TFA salt form further enhances handling and experimental use. Foxy-5 TFA is widely employed in cancer, developmental biology, and regenerative medicine research, providing a precise tool to investigate Wnt signaling, tumor suppression, and therapeutic strategies targeting cell differentiation and tissue remodeling.
| Synonyms | (2S)-2-[[(2S)-4-carboxy-2-[[(2R)-2-[[2-[[(2S)-3-carboxy-2-[[(2S)-2-formamido-4-methylsulfanylbutanoyl]amino]propanoyl]amino]acetyl]amino]-3-sulfanylpropanoyl]amino]butanoyl]amino]-4-methylpentanoic acid;2,2,2-trifluoroacetic acid |
| Molecular Formula | C28H43F3N6O14S2 |
| Purity | ≥95% |
| IUPAC Name | (2S)-2-[[(2S)-4-carboxy-2-[[(2R)-2-[[2-[[(2S)-3-carboxy-2-[[(2S)-2-formamido-4-methylsulfanylbutanoyl]amino]propanoyl]amino]acetyl]amino]-3-sulfanylpropanoyl]amino]butanoyl]amino]-4-methylpentanoic acid;2,2,2-trifluoroacetic acid |
| InChI | InChI=1S/C26H42N6O12S2.C2HF3O2/c1-13(2)8-17(26(43)44)32-24(41)15(4-5-20(35)36)30-25(42)18(11-45)29-19(34)10-27-22(39)16(9-21(37)38)31-23(40)14(28-12-33)6-7-46-3;3-2(4,5)1(6)7/h12-18,45H,4-11H2,1-3H3,(H,27,39)(H,28,33)(H,29,34)(H,30,42)(H,31,40)(H,32,41)(H,35,36)(H,37,38)(H,43,44);(H,6,7)/t14-,15-,16-,17-,18-;/m0./s1 |
| InChIKey | CLBGNYFFUUHBLL-HGIJKBOGSA-N |
| SMILES | CC(C)C[C@@H](C(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CS)NC(=O)CNC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCSC)NC=O.C(=O)(C(F)(F)F)O |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
