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Fmoc-NH-PEG1-C2-acid

Fmoc-NH-PEG1-C2-acid

  • CAT Number: I016151
  • CAS Number: 1654740-73-4
  • Molecular Formula: C₂₀H₂₁NO₅
  • Molecular Weight: 355.38
  • Purity: ≥95%
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Fmoc-NH-PEG1-C2-acid (CAT: I016151) is a PEG-based PROTAC linker specifically designed for use in the synthesis of PROTACs. This linker molecule combines a PEG moiety with a C2 spacer and a Fmoc-protected amine group, allowing for the efficient conjugation of various target-binding ligands or other functional groups to create PROTAC molecules. PROTACs are innovative compounds used to degrade specific target proteins by leveraging the cellular ubiquitin-proteasome system, and this linker plays a crucial role in connecting the key components of the PROTAC construct.

Catalog Number I016151
CAS Number 1654740-73-4
Molecular Formula

C₂₀H₂₁NO₅

Purity 95%
Reference

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

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