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FMOC-ARG(BOC)2-OH

FMOC-ARG(BOC)2-OH

  • CAT Number: M104650
  • CAS Number: 143824-77-5
  • Molecular Formula: C31H40N4O8
  • Molecular Weight: 596.67
  • Purity: ≥95%
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FMOC-ARG(BOC)2-OH (CAS&nbsp;143824-77-5) is<span style="font-family:arial,helvetica,sans-serif;"><span style="font-size:12px;"> a<span style="font-variant-ligatures: normal; orphans: 2; widows: 2;">n excellent derivative for Fmoc SPPS of Arg-containing peptides. Coupling of this derivative can be effected using standard activation methods, such as PyBOP</span><sup style="font-size: 10.8px; color: rgb(102, 94, 88); font-family: Arial, Helvetica, sans-serif; font-variant-ligatures: normal; orphans: 2; widows: 2;">&reg;</sup><span style="font-variant-ligatures: normal; orphans: 2; widows: 2;">&nbsp;or TBTU, although longer reaction times may be necessary due to the bulkiness of the side-chain protection.</span></span></span>

Catalog Number M104650
CAS Number 143824-77-5
Molecular Formula

C31H40N4O8

Purity 95%
Storage Store at -20C
IUPAC Name (2S)-5-[bis[(2-methylpropan-2-yl)oxycarbonylamino]methylideneamino]-2-(9H-fluoren-9-ylmethoxycarbonylamino)pentanoic acid
InChI InChI=1S/C31H40N4O8/c1-30(2,3)42-28(39)34-26(35-29(40)43-31(4,5)6)32-17-11-16-24(25(36)37)33-27(38)41-18-23-21-14-9-7-12-19(21)20-13-8-10-15-22(20)23/h7-10,12-15,23-24H,11,16-18H2,1-6H3,(H,33,38)(H,36,37)(H2,32,34,35,39,40)/t24-/m0/s1
InChIKey WPAALELGEWGQEG-DEOSSOPVSA-N
SMILES CC(C)(C)OC(=O)NC(=NCCCC(C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13)NC(=O)OC(C)(C)C
Reference

1.<span style="font-family: Arial, sans-serif; font-size: 13px; font-variant-ligatures: normal; orphans: 2; widows: 2;">Cezari, M. H., and L. Juliano. &quot;Studies on lactam formation during coupling procedures of N alpha-N omega-protected arginine derivatives.&quot;&nbsp;</span><i style="font-family: Arial, sans-serif; font-size: 13px; font-variant-ligatures: normal; orphans: 2; widows: 2;">Peptide research</i><span style="font-family: Arial, sans-serif; font-size: 13px; font-variant-ligatures: normal; orphans: 2; widows: 2;">&nbsp;9.2 (1996): 88-91.</span><br />
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