Fluvastatin sodium

  • CAT Number: I005581
  • CAS Number: 93957-55-2
  • Molecular Formula: C24H25FNO4 • Na
  • Molecular Weight: 433.5
  • Purity: ≥95%
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Fluvastatin sodium (CAT: I005581) is a medication belonging to the class of statins, which are commonly used to lower cholesterol levels in the body. Fluvastatin works by inhibiting the enzyme HMG-CoA reductase, which plays a key role in cholesterol synthesis. By reducing the production of cholesterol, fluvastatin helps to lower total cholesterol and low-density lipoprotein (LDL) cholesterol levels in the blood. It is primarily prescribed for the treatment of hypercholesterolemia and to reduce the risk of cardiovascular events in patients with a history of coronary artery disease.

Catalog Number I005581
CAS Number 93957-55-2
Molecular Formula

C24H25FNO4 • Na

Purity 95%
Target HMG-CoA Reductase
Solubility 10 mM in DMSO
Storage 3 years -20C powder
InChIKey ZGGHKIMDNBDHJB-CALJPSDSSA-M
Reference

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[1]. Araújo FA, Rocha MA, Capettini LS, et al. 3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitor (fluvastatin) decreases inflammatory angiogenesis in mice. APMIS. 2012 24. [Epub ahead of print]&nbsp;
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[2]. Makabe S, Takahashi Y, Watanabe H, et al. Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway. Atherosclerosis. 2010 Dec;213(2):377-84.&nbsp;
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[3]. Zhang W, Wu J, Zhou L, et al. Fluvastatin, a lipophilic statin, induces apoptosis in human hepatocellular carcinoma cells through mitochondria-operated pathway. Indian J Exp Biol. 2010 Dec;48(12):1167-74.&nbsp;
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[4]. Scripture CD, Pieper JA. Clinical pharmacokinetics of fluvastatin. Clin Pharmacokinet. 2001;40(4):263-81.
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