Flumazenil

• CAT Number: A000422
• CAS Number: 78755-81-4
• Molecular Formula: C15H14FN3O3
• Molecular Weight: 303.3
• Purity: ≥95%
• Target: GABA Receptor
• Solubility: Limited solubility
• Storage: -20°C
• IUPAC Name: ethyl 8-fluoro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate
• InChI: InChI=1S/C15H14FN3O3/c1-3-22-15(21)13-12-7-18(2)14(20)10-6-9(16)4-5-11(10)19(12)8-17-13/h4-6,8H,3,7H2,1-2H3
• InChIKey: OFBIFZUFASYYRE-UHFFFAOYSA-N
• SMILES: CCOC(=O)C1=C2CN(C(=O)C3=C(N2C=N1)C=CC(=C3)F)C

Flumazenil (CAS 78755-81-4) is a specific benzodiazepine receptor antagonist primarily administered by injection. It is the only benzodiazepine receptor antagonist on the market today. Flumazenil is of benefit in patients who become excessively drowsy after benzodiazepines are used for either diagnostic or therapeutic procedures and it has been used as an antidote in the treatment of benzodiazepine overdoses.

Overview of Clinical Research

Flumazenil is a GABA-A receptor antagonist used as antidote for benzodiazepine overdoses. Coeruleus has patents pending for flumazenil in world including Japan in 2020.

Reference

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