Flubendazole-d3

• CAT Number: C000663
• CAS Number: 1173021-08-3
• Molecular Formula: C₁₆H₉D₃FN₃O₃
• Molecular Weight: 316.3
• Purity: ≥95%
• Synonyms: Trideuteriomethyl N-[5-(4-Fluorobenzoyl)-1H-benzimidazol-2-yl]carbamate
• Solubility: DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)
• Storage: -20°C
• IUPAC Name: trideuteriomethyl N-[6-(4-fluorobenzoyl)-1H-benzimidazol-2-yl]carbamate
• InChI: InChI=1S/C16H12FN3O3/c1-23-16(22)20-15-18-12-7-4-10(8-13(12)19-15)14(21)9-2-5-11(17)6-3-9/h2-8H,1H3,(H2,18,19,20,22)/i1D3
• InChIKey: CPEUVMUXAHMANV-FIBGUPNXSA-N
• SMILES: COC(=O)NC1=NC2=C(N1)C=C(C=C2)C(=O)C3=CC=C(C=C3)F

Flubendazole-d3 (Cat No.:C000663) is a deuterium-labeled derivative of flubendazole, a benzimidazole anthelmintic used to treat various parasitic infections. Deuterium substitution enhances molecular stability and provides a labeled version for research purposes. Flubendazole acts by disrupting the microtubule structure in parasites, inhibiting their growth and reproduction. The deuterium labeling allows for precise tracking and analysis, contributing to a deeper understanding of flubendazole’s mechanism of action and potential applications in controlling parasitic diseases.

Reference

Thienpont, D., et al.: Arzneimittel-Forsch., 28, 605 (1978), Vanparijs, O., et al.: Vet. Parasitol, 5, 237 (1979),