FL118-14-Propanol

For research use only. Not for therapeutic Use.

  • CAT Number: I040531
  • CAS Number: 2821768-98-1
  • Molecular Formula: C24H22N2O7
  • Molecular Weight: 450.44
  • Purity: ≥95%
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FL118-14-Propanol(CAT: I040531) is a derivative of the potent anticancer agent FL118, structurally modified with a 1-propanol moiety to enhance solubility and pharmacokinetic properties. Like its parent compound, FL118-14-Propanol selectively inhibits key oncogenic proteins such as survivin, Mcl-1, XIAP, and cIAP2, contributing to its strong pro-apoptotic and antiproliferative effects in cancer cells. This compound shows promise in overcoming drug resistance and enhancing tumor selectivity, making it an attractive candidate for preclinical cancer research. FL118-14-Propanol is ideal for exploring structure–activity relationships and developing next-generation therapeutics targeting apoptosis pathways. Offered in high purity for oncology-focused biochemical and pharmacological investigations.


CAS Number 2821768-98-1
Synonyms

(5S)-5-ethyl-5-hydroxy-14-(3-hydroxypropyl)-7,18,20-trioxa-11,24-diazahexacyclo[11.11.0.02,11.04,9.015,23.017,21]tetracosa-1(24),2,4(9),13,15,17(21),22-heptaene-6,10-dione

Molecular Formula C24H22N2O7
Purity ≥95%
IUPAC Name (5S)-5-ethyl-5-hydroxy-14-(3-hydroxypropyl)-7,18,20-trioxa-11,24-diazahexacyclo[11.11.0.02,11.04,9.015,23.017,21]tetracosa-1(24),2,4(9),13,15,17(21),22-heptaene-6,10-dione
InChI InChI=1S/C24H22N2O7/c1-2-24(30)16-7-18-21-14(9-26(18)22(28)15(16)10-31-23(24)29)12(4-3-5-27)13-6-19-20(33-11-32-19)8-17(13)25-21/h6-8,27,30H,2-5,9-11H2,1H3/t24-/m0/s1
InChIKey CUXVKKNRAHURNN-DEOSSOPVSA-N
SMILES CCC1(C2=C(COC1=O)C(=O)N3CC4=C(C5=CC6=C(C=C5N=C4C3=C2)OCO6)CCCO)O
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