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FK-330

FK-330

  • CAT Number: I006800
  • CAS Number: 442198-67-6 (FK-330) ; 682813-92-9(FK-330 dihydrate)
  • Molecular Formula: C29H28ClF3N6O4
  • Molecular Weight: 617.02
  • Purity: ≥95%
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FK-330 is a novel inducible nitric oxide synthase inhibitor. It prevents ischemia and reperfusion injury in rat liver transplantation.

Catalog Number I006800
CAS Number 442198-67-6 (FK-330) ; 682813-92-9(FK-330 dihydrate)
Synonyms

FK-330; FK 330; FK330; UNII-K47C68D94B; FR-260330; SCHEMBL4918744; K47C68D94B; FK-330; LS-192510.;2-Pyridinepropanamide, alpha-(((2E)-3-(4-chlorophenyl)-1-oxo-2-propen-1-yl)amino)-N-(2-oxo-2-(4-((6-(trifluoromethyl)-4-pyrimidinyl)oxy)-1-piperidinyl)e

Molecular Formula

C29H28ClF3N6O4

Purity 95%
Target nitric oxide synthase inhibitor
Solubility Soluble in DMSO, not in water
Storage 0 - 4°C for short term or -20 °C for long term
SMILES c1ccnc(c1)C[C@@H](C(=O)NCC(=O)N2CCC(CC2)Oc3cc(ncn3)C(F)(F)F)NC(=O)/C=C/c4ccc(cc4)Cl
Reference

</br>1:Tsuchihashi S, Kaldas F, Chida N, Sudo Y, Tamura K, Zhai Y, Qiao B, Busuttil RW, Kupiec-Weglinski JW. FK330, a novel inducible nitric oxide synthase inhibitor, prevents ischemia and reperfusion injury in rat liver transplantation. Am J Transplant. 2006 Sep;6(9):2013-22. Epub 2006 Jun 22. PubMed PMID: 16796718.

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