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FIN56

FIN56

  • CAT Number: I006794
  • CAS Number: 1083162-61-1
  • Molecular Formula: C25H31N3O5S2
  • Molecular Weight: 517.66
  • Purity: ≥95%
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FIN56 (Cat.No:I006794) is a specific inducer of ferroptosis, a non-apoptotic form of cell death characterized by iron-dependent accumulation of lipid peroxidation products and lethal reactive oxygen species (ROS).

Catalog Number I006794
CAS Number 1083162-61-1
Synonyms

FIN56; FIN-56; FIN 56.;N2,N7-Dicyclohexyl-9-(hydroxyimino)-9H-fluorene-2,7-disulfonamide

Molecular Formula

C25H31N3O5S2

Purity 95%
Solubility Soluble in DMSO
Storage 0 - 4°C for short term or -20 °C for long term
IUPAC Name 2-N,7-N-dicyclohexyl-9-hydroxyiminofluorene-2,7-disulfonamide
InChI InChI=1S/C25H31N3O5S2/c29-26-25-23-15-19(34(30,31)27-17-7-3-1-4-8-17)11-13-21(23)22-14-12-20(16-24(22)25)35(32,33)28-18-9-5-2-6-10-18/h11-18,27-29H,1-10H2
InChIKey JLCFMMIWBSZOIS-UHFFFAOYSA-N
SMILES O=S(C1=CC(/C2=NO)=C(C3=C2C=C(S(=O)(NC4CCCCC4)=O)C=C3)C=C1)(NC5CCCCC5)=O
Reference

</br>1:Shimada K, Skouta R, Kaplan A, Yang WS, Hayano M, Dixon SJ, Brown LM, Valenzuela CA, Wolpaw AJ, Stockwell BR. Global survey of cell death mechanisms reveals metabolic regulation of ferroptosis. Nat Chem Biol. 2016 Jul;12(7):497-503. doi: 10.1038/nchembio.2079. Epub 2016 May 9. PubMed PMID: 27159577; PubMed Central PMCID: PMC4920070.

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