FICZ - CAS 172922-91-7

FICZ (6-Formylindolo[3,2-b]carbazole)(CAT: I002250) is a tryptophan-derived ligand that specifically binds to the aryl hydrocarbon receptor (AhR), a transcription factor involved in regulating gene expression. FICZ is known for its high affinity for AhR and its potent induction of CYP1A1 gene expression, which is mediated by AhR activation. It has been used in studies to investigate the role of AhR in various biological processes, including immune responses, metabolism, and detoxification pathways. FICZ has also shown inhibitory activity on CYP1A1 enzyme, making it a valuable tool for studying AhR-mediated effects on gene expression and metabolism.

Catalog Number: I002250

CAS Number: 172922-91-7

PubChem Substance ID:355049547

Molecular Formula: C19H12N2O

Molecular Weight:284.3

Purity: ≥95%

* For research use only. Not for human or veterinary use.

Synonym

Synonyms5,11-dihydroindolo[3,2-b]carbazole-6-carbaldehyde

Property

Molecular Formula: C19H12N2O
Molecular Weight284.3
Target:AhR
SolubilityDMSO: ≤ 10 mg/mL
Purity≥95%
StorageStore at -20°C

Computed Descriptor

InChIInChI=1S/C19H12N2O/c22-10-14-18-12-6-2-4-8-16(12)20-17(18)9-13-11-5-1-3-7-15(11)21-19(13)14/h1-10,20-21H
InChIKeyZUDXFBWDXVNRKF-UHFFFAOYSA-N
SMILES[H]C(C1=C2C(C(C=CC=C3)=C3N2)=CC4=C1C(C=CC=C5)=C5N4)=O