Fexofenadine HCl - CAS 153439-40-8

Fexofenadine HCl (CAT: A000215) is an antihistamine medication used to relieve allergy symptoms. It is commonly used to treat conditions such as seasonal allergic rhinitis (hay fever) and chronic idiopathic urticaria (hives). Fexofenadine works by blocking the effects of histamine, a substance produced by the body during an allergic reaction. By inhibiting histamine’s action, it helps alleviate symptoms like sneezing, runny nose, itchy or watery eyes, and itching of the throat or nose.

Catalog Number: A000215

CAS Number: 153439-40-8

PubChem Substance ID:355037900

Molecular Formula: C32H39NO4 • HCl

Molecular Weight:538.1

Purity: ≥95%

* For research use only. Not for human or veterinary use.

Synonym

SynonymsMDL 16455A

Property

Molecular Formula: C32H39NO4 • HCl
Molecular Weight538.1
Target:Histamine Receptor
SolubilitySoluble in DMSO > 10 mM
Purity≥95%
Storage3 years -20C powder
Overview of Clinical Research<p> Fexofenadine is a&nbsp;<span style=”font-family:arial,helvetica,sans-serif;”><span style=”font-size:12px;”><span style=”orphans: 2; widows: 2;”>histamine H1 receptor antagonist.&nbsp;</span><span style=”font-variant-ligatures: normal; orphans: 2; widows: 2;”>Sanofi completed a phase III trial in Seasonal allergic rhinitis in Canada (PO) (NCT03664882) in 2019.</span></span></span></p> <ul class=”data-list__content” id=”at-a-glance_orphanStatus” style=”list-style: none; margin: 0px; padding-right: 0px; padding-left: 0px; color: rgb(51, 51, 51); font-family: &quot;Helvetica Neue&quot;, Helvetica, Arial, sans-serif; font-size: 13px; font-variant-ligatures: normal; orphans: 2; widows: 2;”> <li class=”data-list__property” style=”list-style: none; zoom: 1; margin-bottom: 10px;”> &nbsp;</li> </ul>

Computed Descriptor

IUPAC Name2-[4-[1-hydroxy-4-[4-[hydroxy(diphenyl)methyl]piperidin-1-yl]butyl]phenyl]-2-methylpropanoic acid;hydrochloride
InChIInChI=1S/C32H39NO4.ClH/c1-31(2,30(35)36)25-17-15-24(16-18-25)29(34)14-9-21-33-22-19-28(20-23-33)32(37,26-10-5-3-6-11-26)27-12-7-4-8-13-27;/h3-8,10-13,15-18,28-29,34,37H,9,14,19-23H2,1-2H3,(H,35,36);1H
InChIKeyRRJFVPUCXDGFJB-UHFFFAOYSA-N
SMILESCC(C)(C1=CC=C(C=C1)C(CCCN2CCC(CC2)C(C3=CC=CC=C3)(C4=CC=CC=C4)O)O)C(=O)O.Cl