Fenofibrate

• CAT Number: A001029
• CAS Number: 49562-28-9
• Molecular Formula: C20H21ClO4
• Molecular Weight: 360.8
• Purity: ≥95%
• Synonyms: 49562-28-9; Procetofen; Lipanthyl; Lipantil; Antara
• Target: PPAR
• Solubility: >12.8mg/mL in DMSO
• Storage: -20°C
• InChI: 1S/C20H21ClO4/c1-13(2)24-19(23)20(3,4)25-17-11-7-15(8-12-17)18(22)14-5-9-16(21)10-6-14/h5-13H,1-4H3
• InChIKey: YMTINGFKWWXKFG-UHFFFAOYSA-N
• SMILES: CC(C)OC(=O)C(C)(C)OC1=CC=C(C=C1)C(=O)C2=CC=C(C=C2)Cl

Fenofibrate (INN) is a drug of the fibrate class. It is mainly used to reduce cholesterol levels in patients at risk of cardiovascular disease. Like other fibrates, it reduces both low-density lipoprotein (LDL) and very low density lipoprotein (VLDL) levels, as well as increasing high-density lipoprotein (HDL) levels and reducing triglyceride levels. It is used alone or along with statins in the treatment of hypercholesterolemia and hypertriglyceridemia. Fenofibrate has been used since 1975, is one of the most commonly prescribed fibrates, and has a well known efficacy and tolerability profile.

Reference

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