For research use only. Not for therapeutic Use.
Etomidate(Cat No.:A000402)is a short-acting intravenous anesthetic agent primarily used for the induction of general anesthesia and sedation in critical care settings. It is favored for its rapid onset, minimal cardiovascular effects, and short duration of action. Etomidate works by enhancing the activity of GABA receptors in the central nervous system, leading to sedation and hypnosis. It appears as a clear, colorless solution and is commonly used in emergency procedures where hemodynamic stability is crucial. While effective, prolonged use can suppress adrenal function, limiting its application to short-term or single-dose administration.
CAS Number | 33125-97-2 |
Synonyms | 33125-97-2; (+)-Etomidate; Amidate; Etomidato; Etomidatum |
Molecular Formula | C14H16N2O2 |
Purity | ≥95% |
Target | GABA Receptor |
Solubility | >12.2mg/mL in DMSO |
Storage | -20°C |
IUPAC Name | ethyl 3-[(1R)-1-phenylethyl]imidazole-4-carboxylate |
InChI | InChI=1S/C14H16N2O2/c1-3-18-14(17)13-9-15-10-16(13)11(2)12-7-5-4-6-8-12/h4-11H,3H2,1-2H3/t11-/m1/s1 |
InChIKey | NPUKDXXFDDZOKR-LLVKDONJSA-N |
SMILES | CCOC(=O)C1=CN=CN1[C@H](C)C2=CC=CC=C2 |
Reference | 1: An X, Li C, Sahebally Z, Wen X, Zhao B, Fang X. Pretreatment with Oxycodone 2: Soleimani A, Heidari N, Habibi MR, Kiabi FH, Khademloo M, Emami Zeydi A, 3: Sanri E, Karacabey S, Akoglu H, Kaya B, Guneysel O. Comparison of <br> <br> <br> 7: Dyer O. Florida executes prisoner with etomidate despite drug maker/’s 8: Saliminia A, Azimaraghi O, Javadi A, Abdoulahpoor M, Movafegh A. [Comparison <br> 10: Wang B, Chen S, Yang J, Yang L, Liu J, Zhang W. ET-26 hydrochloride (ET-26 |
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