Ethyl Vanillate

• CAT Number: I017984
• CAS Number: 617-05-0
• Molecular Formula: C₁₀H₁₂O₄
• Molecular Weight: 196.2
• Purity: ≥95%
• Storage: Room Temperature
• IUPAC Name: ethyl 4-hydroxy-3-methoxybenzoate
• InChI: InChI=1S/C10H12O4/c1-3-14-10(12)7-4-5-8(11)9(6-7)13-2/h4-6,11H,3H2,1-2H3
• InChIKey: MWAYRGBWOVHDDZ-UHFFFAOYSA-N
• SMILES: CCOC(=O)C1=CC(=C(C=C1)O)OC

Ethyl vanillin（Cat No.:I017984）, also known as Bourbonal or Ethylprotal, is an analog of vanillin commonly utilized as a flavoring agent and fungicide. It exhibits potent antioxidant activity, making it useful for preserving food products and extending their shelf life. Additionally, ethyl vanillin has been found to inhibit the enzyme 17β-HSD2, with an IC50 value of 1.3 µM. This inhibition of 17β-HSD2 can have implications in various biological processes and may be relevant in the development of therapeutics targeting conditions influenced by this enzyme, such as hormone-related disorders.

Reference

[1]. Engeli RT, et al. Interference of Paraben Compounds with Estrogen Metabolism by Inhibition of 17β-Hydroxysteroid Dehydrogenases. Int J Mol Sci. 2017 Sep 19;18(9). pii: E2007.[2]. COHEN R, et al. Four new fungicides for Coccidioides immitis: 1. Sodium caprylate. 2. Ethyl vanillate 3. Fradicin. 4. Thiolutin. Arch Pediatr. 1951 Jun;68(6):259-64.