Escitalopram

• CAT Number: I001111
• CAS Number: 128196-01-0
• Molecular Formula: C20H21FN2O
• Molecular Weight: 324.4
• Purity: ≥95%
• Target: SSRIs
• Solubility: 10 mM in DMSO
• Storage: Store at -20℃
• IUPAC Name: (1S)-1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-3H-2-benzofuran-5-carbonitrile
• InChI: InChI=1S/C20H21FN2O/c1-23(2)11-3-10-20(17-5-7-18(21)8-6-17)19-9-4-15(13-22)12-16(19)14-24-20/h4-9,12H,3,10-11,14H2,1-2H3/t20-/m0/s1
• InChIKey: WSEQXVZVJXJVFP-FQEVSTJZSA-N
• SMILES: CN(C)CCC[C@@]1(C2=C(CO1)C=C(C=C2)C#N)C3=CC=C(C=C3)F

Escitalopram (Cat.No:I001111) is an antidepressant medication belonging to the selective serotonin reuptake inhibitor (SSRI) class. It is primarily used for the treatment of major depressive disorder and generalized anxiety disorder. Escitalopram works by increasing the levels of serotonin, a neurotransmitter associated with mood regulation, in the brain.

Reference

[1]. Zhang, P., et al., Structure-activity relationships for a novel series of citalopram (1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbon itrile) analogues at monoamine transporters. J Med Chem, 2010. 53(16): p. 6112-21.
[2]. Pastoor, D. and J. Gobburu, Clinical pharmacology review of escitalopram for the treatment of depression. Expert Opin Drug Metab Toxicol, 2014. 10(1): p. 121-8.