Epsilon-V1-2

• CAT Number: R026982
• CAS Number: 182683-50-7
• Molecular Formula: C37H65N9O13
• Molecular Weight: 843.96
• Purity: ≥95%
• Synonyms: (4S)-4-amino-5-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-6-amino-1-[(2S)-2-[[(1S,2R)-1-carboxy-2-hydroxypropyl]carbamoyl]pyrrolidin-1-yl]-1-oxohexan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]amino]-5-oxopentanoic acid
• InChI: InChI=1S/C37H65N9O13/c1-18(2)16-24(32(53)41-23(10-7-8-14-38)36(57)46-15-9-11-26(46)34(55)45-29(21(6)48)37(58)59)42-33(54)25(17-47)43-35(56)28(19(3)4)44-30(51)20(5)40-31(52)22(39)12-13-27(49)50/h18-26,28-29,47-48H,7-17,38-39H2,1-6H3,(H,40,52)(H,41,53)(H,42,54)(H,43,56)(H,44,51)(H,45,55)(H,49,50)(H,58,59)/t20-,21+,22-,23-,24-,25-,26-,28-,29-/m0/s1
• InChIKey: KNTBAGOTDJPUJV-XMTFRXHISA-N
• SMILES: C[C@H]([C@@H](C(=O)O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](C(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(=O)O)N)O

Epsilon-V1-2（Cat No.:R026982）is a synthetic peptide inhibitor that selectively targets the epsilon isoform of protein kinase C (PKCε), a signaling molecule involved in cardiac protection, pain modulation, and cellular survival pathways. By disrupting the interaction between PKCε and its receptor for activated C-kinase (RACK), Epsilon-V1-2 blocks PKCε translocation and downstream signaling without affecting other PKC isoforms. This makes it a valuable tool in cardiovascular and neurobiological research, particularly in models of ischemia-reperfusion injury and chronic pain. Epsilon-V1-2 is widely used to dissect PKCε-specific roles in signal transduction and therapeutic development.