For research use only. Not for therapeutic Use.
Epimestrol(CAT: I026930) is a synthetic estrogen derivative and a prodrug of 17-epiestriol, structurally related to natural estriol. It is primarily used for hormonal therapy, especially in the treatment of ovulatory disorders and menstrual irregularities. As a weak estrogen, Epimestrol offers controlled hormonal modulation with a favorable safety profile. It exerts its effects by binding to estrogen receptors and regulating feedback mechanisms in the hypothalamic-pituitary-gonadal axis. Due to its predictable pharmacokinetics and minimal androgenic activity, Epimestrol is also studied for use in fertility enhancement protocols and menopausal support. It is typically administered orally under clinical supervision in gynecological settings.
| CAS Number | 7004-98-0 |
| Synonyms | Epimestrol; Epimestrolo; Epimestrolum; NSC 55975; NSC55975; NSC-55975; Org 817; Org-817; Stimovul; |
| Molecular Formula | C19H26O3 |
| Purity | 98% |
| Solubility | To be determined |
| Appearance | Solid powder |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| IUPAC Name | (8R,9S,13S,14S,16R,17S)-3-methoxy-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-16,17-diol |
| InChI | InChI=1S/C19H26O3/c1-19-8-7-14-13-6-4-12(22-2)9-11(13)3-5-15(14)16(19)10-17(20)18(19)21/h4,6,9,14-18,20-21H,3,5,7-8,10H2,1-2H3/t14-,15-,16+,17-,18-,19+/m1/s1 |
| InChIKey | UHQGCIIQUZBJAE-RRQVMCLOSA-N |
| SMILES | C[C@]12CC[C@H]3[C@H]([C@@H]1C[C@H]([C@H]2O)O)CCC4=C3C=CC(=C4)OC |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
