epi-Canagliflozin

• CAT Number: C000594
• CAS Number: 1589590-87-3
• Molecular Formula: C₂₄H₂₅FO₅S
• Molecular Weight: 444.52
• Purity: ≥95%
• Solubility: DMSO (Slightly), Methanol (Slightly)
• Storage: -20°C, Hygroscopic

epi-Canagliflozin (CAT: C000594) is an epimeric impurity of Canagliflozin, a sodium/glucose cotransporter 2 (SGLT2) inhibitor used in the management of type 2 diabetes and obesity. Canagliflozin works by inhibiting the reabsorption of glucose in the kidneys, leading to increased glucose excretion in the urine and improved glycemic control. epi-Canagliflozin is a closely related compound that may result from a stereochemical alteration during the synthesis of Canagliflozin.

Reference

Chao, E. et al.: Drug Fut., 36, 351 (2011); Sha, S. et al.: Diab. Obes. Metab., 13, 669 (2011); Kipnes, M.S.: Clin. Invest., 1, 145 (2011);