Endosidin-2

• CAT Number: R067046
• CAS Number: 1839524-44-5
• Molecular Formula: C15H12FIN2O3
• Molecular Weight: 414.17
• Purity: ≥95%

Endosidin2 (ES2) binds to the exocyst component of 70 kDa (EXO70) subunit of the exocyst complex with a Kd of 253 μM. Endosidin2 inhibits exocytosis and endosomal recycling in both plant and human cells and enhances plant vacuolar trafficking. Endosidin2 is a valuable new tool for the study of exocytosis[1].

Reference

[1]. Zhang C, et al. Endosidin2 targets conserved exocyst complex subunit EXO70 to inhibit exocytosis. Proc Natl Acad Sci U S A. 2016 Jan 5;113(1):E41-50.
 [Content Brief]