For research use only. Not for therapeutic Use.
Encainide (Cat No.: I026842) is a class Ic antiarrhythmic drug that blocks fast sodium channels in cardiac myocytes, slowing phase 0 depolarization and conduction velocity without significantly affecting repolarization. It is used to treat and prevent life-threatening ventricular arrhythmias but is generally reserved for severe cases due to proarrhythmic risk. Encainide is metabolized in the liver to active metabolites that contribute to its antiarrhythmic effects. Its use requires careful monitoring of cardiac function and ECG parameters to avoid adverse effects such as arrhythmia exacerbation or conduction block.
| CAS Number | 66778-36-7 |
| Synonyms | 4-methoxy-N-[2-[2-(1-methylpiperidin-2-yl)ethyl]phenyl]benzamide |
| Molecular Formula | C22H28N2O2 |
| Purity | ≥95% |
| InChI | InChI=1S/C22H28N2O2/c1-24-16-6-5-8-19(24)13-10-17-7-3-4-9-21(17)23-22(25)18-11-14-20(26-2)15-12-18/h3-4,7,9,11-12,14-15,19H,5-6,8,10,13,16H2,1-2H3,(H,23,25) |
| InChIKey | PJWPNDMDCLXCOM-UHFFFAOYSA-N |
| SMILES | CN1CCCCC1CCC2=CC=CC=C2NC(=O)C3=CC=C(C=C3)OC |
| Reference | [1]. R N Brogden, et al. Encainide. A review of its pharmacological properties and therapeutic efficacy. Drugs. 1987 Nov;34(5):519-38. |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
