• CAT Number: I017422
  • CAS Number: 1446350-60-2
  • Molecular Formula: C₃₉H₃₇N₃O₃
  • Molecular Weight: 595.73
  • Purity: ≥95%
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TCH-165(CAT: I017422) is a tetrahydroisoquinoline-based drug that selectively inhibits the phosphodiesterase 4 (PDE4) enzyme. By inhibiting PDE4, TCH-165 has the potential to be used as a treatment for inflammatory diseases such as asthma, COPD, and IBD. In preclinical studies, TCH-165 has shown potent anti-inflammatory activity in various disease models. However, further clinical development is needed to determine its safety and efficacy in humans. TCH-165 should only be used for research purposes.

Catalog Number I017422
CAS Number 1446350-60-2
Molecular Formula


Purity 95%

[1]. Njomen E, et al. Small Molecule Modulation of Proteasome Assembly. Biochemistry. 2018 Jul 17;57(28):4214-4224.

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