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EIPA hydrochloride

EIPA hydrochloride

  • CAT Number: I019130
  • CAS Number: 1345839-28-2
  • Molecular Formula: C₁₁H₁₉Cl₂N₇O
  • Molecular Weight: 336.22
  • Purity: ≥95%
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EIPA hydrochloride (Cat No.:I019130) is a TRPP3 channel inhibitor with an IC50 of 10.5 μM. EIPA hydrochloride also inhibits the Na+/H+ exchanger (NHE) and macrophages. If you need, please contact us in time, and we will reply as soon as possible within 24 hours.

Catalog Number I019130
CAS Number 1345839-28-2
Molecular Formula

C₁₁H₁₉Cl₂N₇O

Purity 95%
Storage Store at -20°C
IUPAC Name 3-amino-6-chloro-N-(diaminomethylidene)-5-[ethyl(propan-2-yl)amino]pyrazine-2-carboxamide;hydrochloride
InChI InChI=1S/C11H18ClN7O.ClH/c1-4-19(5(2)3)9-7(12)16-6(8(13)17-9)10(20)18-11(14)15;/h5H,4H2,1-3H3,(H2,13,17)(H4,14,15,18,20);1H
InChIKey BGHBOQNLQNKPFO-UHFFFAOYSA-N
SMILES CCN(C1=NC(=C(N=C1Cl)C(=O)N=C(N)N)N)C(C)C.Cl
Reference

[1]. Dai XQ, et al. Inhibition of TRPP3 channel by MK-870 and analogs. Mol Pharmacol. 2007 Dec;72(6):1576-85.<br>[2]. Shi H, et al. Na+/H+ Exchanger Regulates Amino Acid-Mediated Autophagy in Intestinal Epithelial Cells. Cell Physiol Biochem. 2017;42(6):2418-2429.<br>[3]. Zhu BY, et al. A new HDAC inhibitor cinnamoylphenazine shows antitumor activity in association with intensive macropinocytosis.

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