For research use only. Not for therapeutic Use.
Edpetiline (Cat No.:R072719) is a steroidal alkaloid glycoside isolated from Fritillaria species. It exhibits notable pharmacological activities, particularly anti-inflammatory, antioxidant, and respiratory protective effects. Studies show Edpetiline suppresses pro-inflammatory cytokines such as TNF-α and IL-6, reduces reactive oxygen species, and inhibits NF-κB translocation along with p38 and ERK MAPK pathways. Additionally, it demonstrates antitussive, expectorant, spasmolytic, antibacterial, and antihypertensive properties. These multifaceted bioactivities make Edpetiline a promising natural compound for research in inflammation, respiratory diseases, and cardiovascular disorders, supporting its potential as a therapeutic lead.
| CAS Number | 32685-93-1 |
| Synonyms | (1R,2S,6S,9S,10S,11S,14S,15S,18S,20S,23R,24S)-10-hydroxy-6,10,23-trimethyl-20-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4-azahexacyclo[12.11.0.02,11.04,9.015,24.018,23]pentacosan-17-one |
| Molecular Formula | C33H53NO8 |
| Purity | ≥95% |
| IUPAC Name | (1R,2S,6S,9S,10S,11S,14S,15S,18S,20S,23R,24S)-10-hydroxy-6,10,23-trimethyl-20-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4-azahexacyclo[12.11.0.02,11.04,9.015,24.018,23]pentacosan-17-one |
| InChI | InChI=1S/C33H53NO8/c1-16-4-7-27-33(3,40)22-6-5-18-19(21(22)14-34(27)13-16)11-23-20(18)12-25(36)24-10-17(8-9-32(23,24)2)41-31-30(39)29(38)28(37)26(15-35)42-31/h16-24,26-31,35,37-40H,4-15H2,1-3H3/t16-,17-,18+,19+,20-,21-,22-,23-,24+,26+,27-,28+,29-,30+,31+,32+,33-/m0/s1 |
| InChIKey | DHQFYEJMFMYGCV-RRIRULBESA-N |
| SMILES | C[C@H]1CC[C@H]2[C@@]([C@H]3CC[C@@H]4[C@H]([C@@H]3CN2C1)C[C@H]5[C@H]4CC(=O)[C@@H]6[C@@]5(CC[C@@H](C6)O[C@H]7[C@@H]([C@H]([C@@H]([C@H](O7)CO)O)O)O)C)(C)O |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
