EBE-A22

  • CAT Number: I002750
  • CAS Number: 229476-53-3
  • Molecular Formula: C17H16BrN3O2
  • Molecular Weight: 374.23
  • Purity: ≥95%
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EBE-A22(Cat No.: I002750), is a derivative of PD 153035. While PD 153035 is known for its ability to inhibit the phosphorylation of ErbB-1 (also known as EGFR), EBE-A22 does not exhibit this property. The differentiation between these compounds in terms of ErbB-1 phosphorylation inhibition suggests that EBE-A22 may have unique characteristics or molecular interactions, making it valuable for research aimed at understanding receptor tyrosine kinase signaling pathways. Should you require further information or support regarding EBE-A22, please do not hesitate to contact us.

Catalog Number I002750
CAS Number 229476-53-3
Molecular Formula

C17H16BrN3O2

Purity 95%
Solubility 10 mM in DMSO
Storage Store at -20°C
IUPAC Name N-(3-bromophenyl)-6,7-dimethoxy-N-methylquinazolin-4-amine
InChI InChI=1S/C17H16BrN3O2/c1-21(12-6-4-5-11(18)7-12)17-13-8-15(22-2)16(23-3)9-14(13)19-10-20-17/h4-10H,1-3H3
InChIKey IPWGDOZPSOZFOD-UHFFFAOYSA-N
SMILES CN(C1=CC(=CC=C1)Br)C2=NC=NC3=CC(=C(C=C32)OC)OC
Reference

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<br>[1]. Goossens JF, et al. DNA interaction of the tyrosine protein kinase inhibitor PD153035 and its N-methyl analogue. Biochemistry. 2001 Apr 17;40(15):4663-71.
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