E3 ligase Ligand 4

• CAT Number: I013141
• CAS Number: 835616-60-9
• Molecular Formula: C₁₃H₉FN₂O₄
• Molecular Weight: 276.22
• Purity: ≥95%
• Target: Autophagy
• Solubility: DMSO: 200 mg/mL
• Storage: 2-8°C
• IUPAC Name: 2-(2,6-dioxopiperidin-3-yl)-4-fluoroisoindole-1,3-dione
• InChI: InChI=1S/C13H9FN2O4/c14-7-3-1-2-6-10(7)13(20)16(12(6)19)8-4-5-9(17)15-11(8)18/h1-3,8H,4-5H2,(H,15,17,18)
• InChIKey: CRAUTELYXAAAPW-UHFFFAOYSA-N
• SMILES: C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)F

E3 ligase Ligand 4 (Cat No.:I013141) is a ligand for E3 ubiquitin ligase used in PROTAC technology. Intermediate for the synthesis of N-[2-aminoethyl]pomalomide TFA salt. N-[2-Aminoethyl]pomalidomide TFA is a derivative of thalidomide, an effective inhibitor of TNF-α, and an anti-inflammatory and antineoplastic agent for the treatment of multiple myeloma.