Duloxetine-d7

• CAT Number: R005154
• CAS Number: 919514-01-5
• Molecular Formula: C18H12D7NOS
• Molecular Weight: 304.46
• Purity: ≥95%
• Synonyms: (3S)-3-(2,3,4,5,6,7,8-heptadeuterionaphthalen-1-yl)oxy-N-methyl-3-thiophen-2-ylpropan-1-amine
• InChI: InChI=1S/C18H19NOS/c1-19-12-11-17(18-10-5-13-21-18)20-16-9-4-7-14-6-2-3-8-15(14)16/h2-10,13,17,19H,11-12H2,1H3/t17-/m0/s1/i2D,3D,4D,6D,7D,8D,9D
• InChIKey: ZEUITGRIYCTCEM-KGAVXYHHSA-N
• SMILES: [2H]C1=C(C(=C2C(=C1[2H])C(=C(C(=C2O[C@@H](CCNC)C3=CC=CS3)[2H])[2H])[2H])[2H])[2H]

Duloxetine-d7（Cat No.:R005154）is a deuterium-labeled form of duloxetine, a serotonin-norepinephrine reuptake inhibitor (SNRI) used to treat depression, anxiety, fibromyalgia, and neuropathic pain. It contains seven deuterium atoms, allowing for enhanced stability and precise quantification in mass spectrometry-based pharmacokinetic and metabolic studies. Duloxetine-d7 retains the pharmacological activity of the parent compound, modulating neurotransmitter levels in the central nervous system. It is widely employed as an internal standard in bioanalytical assays to monitor drug levels, study metabolic pathways, and ensure accurate dosing evaluations in clinical and preclinical research without altering therapeutic effects.