For research use only. Not for therapeutic Use.
DTP3 TFA（Cat No.:I046089）is a tripeptide-based small-molecule inhibitor designed to disrupt the interaction between MAP3K (ASK1) and its regulatory protein, thereby selectively blocking the ASK1-dependent apoptosis pathway. By preventing aberrant ASK1 activation, DTP3 induces tumor cell death while sparing normal cells, offering a promising targeted approach in oncology. The trifluoroacetate (TFA) salt form enhances solubility and stability for research use. DTP3 TFA has shown preclinical potential in treating multiple myeloma and other cancers, making it a valuable tool for apoptosis and cancer therapy studies.
| CAS Number | 2759216-46-9 |
| Synonyms | (2R)-2-[[(2R)-2-acetamido-3-(4-hydroxyphenyl)propanoyl]amino]-N-[(2R)-1-amino-1-oxo-3-phenylpropan-2-yl]-5-(diaminomethylideneamino)pentanamide;2,2,2-trifluoroacetic acid |
| Molecular Formula | C28H36F3N7O7 |
| Purity | ≥95% |
| IUPAC Name | (2R)-2-[[(2R)-2-acetamido-3-(4-hydroxyphenyl)propanoyl]amino]-N-[(2R)-1-amino-1-oxo-3-phenylpropan-2-yl]-5-(diaminomethylideneamino)pentanamide;2,2,2-trifluoroacetic acid |
| InChI | InChI=1S/C26H35N7O5.C2HF3O2/c1-16(34)31-22(15-18-9-11-19(35)12-10-18)25(38)32-20(8-5-13-30-26(28)29)24(37)33-21(23(27)36)14-17-6-3-2-4-7-17;3-2(4,5)1(6)7/h2-4,6-7,9-12,20-22,35H,5,8,13-15H2,1H3,(H2,27,36)(H,31,34)(H,32,38)(H,33,37)(H4,28,29,30);(H,6,7)/t20-,21-,22-;/m1./s1 |
| InChIKey | JCVMRDQSOXBZIO-AFYLVLOISA-N |
| SMILES | CC(=O)N[C@H](CC1=CC=C(C=C1)O)C(=O)N[C@H](CCCN=C(N)N)C(=O)N[C@H](CC2=CC=CC=C2)C(=O)N.C(=O)(C(F)(F)F)O |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
