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DS-6051B

DS-6051B

  • CAT Number: I006550
  • Molecular Formula: C15H23N7O4S
  • Purity: ≥95%
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DS-6051B is an orally available inhibitor of the receptor tyrosine kinases C-ros oncogene 1 (ROS1) and the neurotrophic tyrosine receptor kinase (NTRK) types 1, 2 and 3, with potential antineoplastic activity. Upon oral administration, DS-6051b binds to and inhibits ROS1 and the NTRK family members. This inhibition leads to a disruption of ROS1- and NTRK-mediated signaling and eventually inhibits the growth of tumor cells that are overexpressing ROS1 and/or NTRKs. ROS1, overexpressed in certain cancer cells, plays a key role in cell growth and survival of cancer cells. NTRK mutations or rearrangements play a key role in cancer progression.

Catalog Number I006550
Synonyms

DS-6051B; DS 6051B; DS6051B.;Unknown

Molecular Formula

C15H23N7O4S

Purity 95%
Target NTRK/ROS1 inhibitor
Solubility Soluble in DMSO, not in water
Storage 0 - 4°C for short term or -20 °C for long term
SMILES Unknown

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