Droperidol

• CAT Number: A000860
• CAS Number: 548-73-2
• Molecular Formula: C22H22FN3O2
• Molecular Weight: 379.4
• Purity: ≥95%
• Target: D1DR and D2DR inhibitor
• Storage: -20°C
• InChI: InChI=1S/C22H22FN3O2/c23-17-9-7-16(8-10-17)21(27)6-3-13-25-14-11-18(12-15-25)26-20-5-2-1-4-19(20)24-22(26)28/h1-2,4-5,7-11H,3,6,12-15H2,(H,24,28)
• InChIKey: RMEDXOLNCUSCGS-UHFFFAOYSA-N
• SMILES: C1CN(CC=C1N2C3=CC=CC=C3NC2=O)CCCC(=O)C4=CC=C(C=C4)F

Droperidol is a D1DR and D2DR inhibitor, an antidopaminergic drug used as an antiemetic and antipsychotic. Droperidol is also often used for neuroleptanalgesic anesthesia and sedation in intensive-care treatment. It has also been used as an antipsychotic in doses ranging from 5 to 10 mg given as an intramuscular injection, generally in cases of severe agitation in a psychotic patient who is refusing oral medication. Its use in intramuscular sedation has been replaced by intramuscular preparations of haloperidol, midazolam, clonazepam and olanzapine.

Reference

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