DONAXINE iodomethylate

• CAT Number: M144070
• CAS Number: 5457-31-8
• Molecular Formula: C12H17IN2
• Molecular Weight: 316.186
• Purity: ≥95%
• Synonyms: 3-(Dimethylaminomethyl) indole iodmethylate
• Solubility: In ethanol and methanol
• Storage: Store in a dry, cool and dark place
• IUPAC Name: 1H-indol-3-ylmethyl(trimethyl)azanium;iodide
• InChI: InChI=1S/C12H17N2.HI/c1-14(2,3)9-10-8-13-12-7-5-4-6-11(10)12;/h4-8,13H,9H2,1-3H3;1H/q+1;/p-1
• InChIKey: STGYYGWMNTXYAJ-UHFFFAOYSA-M
• SMILES: C[N+](C)(C)CC1=CNC2=CC=CC=C21.[I-]

DONAXINE iodomethylate(cas 5457-31-8) is an analeptic of CNS and a tocolytic Indole alkaloidDerived from the basic alkaloid Donaxine (gramine) extracted from Arundo donax (Gramineae fam.)
It acts on certain subtype of 5HT receptors, is an analeptic of CNS and a tocolytic.
Field of use as a new chemical and pharmacological class of analeptics and tocolytics.
Recommended doses: 0.3-2.0 mg/kg (i.v.)
Recommended concentrations: 3.10-6 – 2.10-5 g/ml

Reference

– Yu.R.Mirzayev et al., /Arundo donax plant as a potential source of serotoninergic compounds/ at the 5-th International Symposium on the Chemistry of Natural Compounds. May 20 ~ 23 , 2003, Tashkent, Uzbekistan, p. 65