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DMCM hydrochloride

DMCM hydrochloride

  • CAT Number: I000815
  • CAS Number: 1215833-62-7
  • Molecular Formula: C17H18N2O4.HCl
  • Molecular Weight: 350.8
  • Purity: ≥95%
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DMCM hydrochloride (Cat No.:I000815) is a benzodiazepine non-selective full inverse agonist. DMCM has affinity for human recombinant GABAA αxβ3γ2 receptor subtype, and the Ki values for α1, α2, α3 and α5 receptors are 10nM, 13nM, 7.5nM, 2.2nM, respectively. If you need, please contact us in time, and we will reply to you as soon as possible within 24 hours.

Catalog Number I000815
CAS Number 1215833-62-7
Molecular Formula

C17H18N2O4.HCl

Purity 95%
Target GABA Receptor
Solubility 35 mg/mL in water and 50 mM in DMSO.
Storage under inert gas (nitrogen or Argon) at 2-8°C
IUPAC Name methyl 4-ethyl-6,7-dimethoxy-9H-pyrido[3,4-b]indole-3-carboxylate;hydrochloride
InChI InChI=1S/C17H18N2O4.ClH/c1-5-9-15-10-6-13(21-2)14(22-3)7-11(10)19-12(15)8-18-16(9)17(20)23-4;/h6-8,19H,5H2,1-4H3;1H
InChIKey FHCRBVQGMZUJKY-UHFFFAOYSA-N
SMILES CCC1=C2C3=CC(=C(C=C3NC2=CN=C1C(=O)OC)OC)OC.Cl
Reference

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<br>[1]. Sieve AN et al. Pain and negative affect: evidence the inverse benzodiazepine agonist DMCM inhibits pain and learning in rats. Psychopharmacology (Berl), 2001 Jan 1, 153(2):180-90.

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