Dimethocaine is a local anesthetic that, because of its similarity in action to cocaine, has potential for abuse. This compound completely inhibits dopamine uptake in rat striatal synaptosomes with an IC<sub>50</sub> value of 1.2 µM comparable to that of cocaine (IC<sub>50</sub> = 0.7 µM). As a result, dimethocaine dose-<wbr></wbr>dependently substitutes for cocaine in drug discrimination tests in rats and rhesus monkeys. This product is intended for forensic and research purposes.
| Catalog Number | R053879 |
| CAS Number | 553-63-9 |
| Synonyms | 1-Aminobenzoyl-2,2-dimethyl-3-diethylaminopropanol Hydrochloride; 3-Diethylamino-2,2-dimethylpropyl p-aminobenzoate Hydrochloride; Diethylaminoneopentyl Alcohol Hydrochloride p-Aminobenzoate; Larocaine Hydrochloride; |
| Molecular Formula | C16H27ClN2O2 |
| Purity | 95% |
| Storage | -20°C |
| IUPAC Name | [3-(diethylamino)-2,2-dimethylpropyl] 4-aminobenzoate;hydrochloride |
| InChI | InChI=1S/C16H26N2O2.ClH/c1-5-18(6-2)11-16(3,4)12-20-15(19)13-7-9-14(17)10-8-13;/h7-10H,5-6,11-12,17H2,1-4H3;1H |
| InChIKey | WWTWKTDXBNHESE-UHFFFAOYSA-N |
| SMILES | CCN(CC)CC(C)(C)COC(=O)C1=CC=C(C=C1)N.Cl |
