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Dihydrorotenone

Dihydrorotenone

  • CAT Number: I017931
  • CAS Number: 6659-45-6
  • Molecular Formula: C₂₃H₂₄O₆
  • Molecular Weight: 396.43
  • Purity: ≥95%
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Dihydrorotenone (Cat No.:I017931) is a natural insecticide and a mitochondrial inhibitor. Dihydrorotenone may induce Parkinsonism. Dihydrorotenone induces apoptosis in human plasma cells by triggering endoplasmic reticulum stress and activating the p38 signaling pathway.

Catalog Number I017931
CAS Number 6659-45-6
Molecular Formula

C₂₃H₂₄O₆

Purity 95%
Storage Store at -20°C
IUPAC Name (1S,6R,13S)-16,17-dimethoxy-6-propan-2-yl-2,7,20-trioxapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),9,14,16,18-hexaen-12-one
InChI InChI=1S/C23H24O6/c1-11(2)16-8-14-15(28-16)6-5-12-22(24)21-13-7-18(25-3)19(26-4)9-17(13)27-10-20(21)29-23(12)14/h5-7,9,11,16,20-21H,8,10H2,1-4H3/t16-,20-,21+/m1/s1
InChIKey DTFARBHXORYQBF-HBGVWJBISA-N
SMILES CC(C)C1CC2=C(O1)C=CC3=C2OC4COC5=CC(=C(C=C5C4C3=O)OC)OC
Reference

[1]. Zhang J, et al. The natural pesticide dihydrorotenone induces human plasma cell apoptosis by triggering endoplasmic reticulum stress and activating p38 signaling pathway. PLoS One. 2013 Jul 26;8(7):e69911.

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