Difopein TFA

• CAT Number: I046096
• Molecular Formula: C275H425N76F3O91S6
• Purity: ≥95%

Difopein TFA（Cat No.:I046096）is a synthetic dimeric peptide inhibitor designed to block 14-3-3 protein interactions, which regulate numerous signaling pathways involved in cell cycle control, apoptosis, and stress responses. By disrupting 14-3-3 binding to phosphorylated partners, difopein modulates downstream signaling, making it a valuable tool for studying protein–protein interactions. The trifluoroacetate (TFA) salt form improves solubility and stability for laboratory use. Difopein TFA is widely applied in cancer, neurobiology, and metabolic research to explore therapeutic strategies targeting dysregulated 14-3-3–mediated signaling in disease contexts.