For research use only. Not for therapeutic Use.
Desmethylcitalopram (DCIT) hydrochloride(CAT: R009140) is the active N-demethylated metabolite of Citalopram, a widely used selective serotonin reuptake inhibitor (SSRI). DCIT retains antidepressant activity, contributing to the therapeutic effects of its parent compound. In addition to its serotonergic action, DCIT acts as an inhibitor of cytochrome P450 enzymes CYP2D6 and CYP2C19, with reported IC₅₀ values of 39.5 μM and 53.5 μM, respectively. This dual pharmacological profile makes it a valuable tool for studying SSRI metabolism, pharmacodynamics, and potential drug–drug interactions. Supplied as a stable hydrochloride salt, DCIT is ideal for neuroscience, psychopharmacology, and metabolic enzyme inhibition research.
| CAS Number | 97743-99-2 |
| Synonyms | 1-(4-fluorophenyl)-1-[3-(methylamino)propyl]-3H-2-benzofuran-5-carbonitrile;hydrochloride |
| Molecular Formula | C19H20ClFN2O |
| Purity | ≥95% |
| IUPAC Name | 1-(4-fluorophenyl)-1-[3-(methylamino)propyl]-3H-2-benzofuran-5-carbonitrile;hydrochloride |
| InChI | InChI=1S/C19H19FN2O.ClH/c1-22-10-2-9-19(16-4-6-17(20)7-5-16)18-8-3-14(12-21)11-15(18)13-23-19;/h3-8,11,22H,2,9-10,13H2,1H3;1H |
| InChIKey | DYIZNULSIBGJPJ-UHFFFAOYSA-N |
| SMILES | CNCCCC1(C2=C(CO1)C=C(C=C2)C#N)C3=CC=C(C=C3)F.Cl |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
