Deslorelin - CAS 57773-65-6
Deslorelin(CAT: I004154) is a synthetic peptide analog of gonadotropin-releasing hormone (GnRH) that is used as a veterinary medicine for the treatment of various reproductive disorders in animals. GnRH is a hormone that plays a key role in regulating the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the pituitary gland, which in turn control the production of sex hormones such as testosterone and estrogen. By acting as a potent agonist of GnRH receptors, Deslorelin can induce a temporary suppression of gonadal function, which is useful in the treatment of conditions such as ovarian cysts, uterine fibroids, and certain forms of cancer. Deslorelin is typically administered as an implant or injection and can have side effects such as local irritation, lethargy, and changes in behavior.
Catalog Number: I004154
CAS Number: 57773-65-6
PubChem Substance ID:355036917
Molecular Formula: C64H83N17O12
Molecular Weight:1282.45
Purity: ≥95%
* For research use only. Not for human or veterinary use.
Synonym
| Synonyms | Somagard; D-Trp LHRH-PEA; Bachem 9022 |
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Property
| Molecular Formula: | C64H83N17O12 |
|---|---|
| Molecular Weight | 1282.45 |
| Solubility | DMSO: ≥ 30 mg/mL |
| Purity | ≥95% |
| Storage | 3 years -20C powder |
| Overview of Clinical Research | <span style=”color:#000000;”><span style=”font-family:arial,helvetica,sans-serif;”><span style=”font-size:12px;”>Deslorelin is a g<span style=”font-variant-ligatures: normal; orphans: 2; widows: 2;”>onadotropin releasing hormone stimulant. It has not been granted for the orphan drug status.</span></span></span></span> |
Computed Descriptor
| IUPAC Name | (2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-5-(diaminomethylideneamino)-1-[(2S)-2-(ethylcarbamoyl)pyrrolidin-1-yl]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide |
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| InChI | InChI=1S/C64H83N17O12/c1-4-68-62(92)53-16-10-24-81(53)63(93)46(15-9-23-69-64(65)66)74-56(86)47(25-35(2)3)75-58(88)49(27-37-30-70-43-13-7-5-11-41(37)43)77-57(87)48(26-36-17-19-40(83)20-18-36)76-61(91)52(33-82)80-59(89)50(28-38-31-71-44-14-8-6-12-42(38)44)78-60(90)51(29-39-32-67-34-72-39)79-55(85)45-21-22-54(84)73-45/h5-8,11-14,17-20,30-32,34-35,45-53,70-71,82-83H,4,9-10,15-16,21-29,33H2,1-3H3,(H,67,72)(H,68,92)(H,73,84)(H,74,86)(H,75,88)(H,76,91)(H,77,87)(H,78,90)(H,79,85)(H,80,89)(H4,65,66,69)/t45-,46-,47-,48-,49+,50-,51-,52-,53-/m0/s1 |
| InChIKey | GJKXGJCSJWBJEZ-XRSSZCMZSA-N |
| SMILES | CCNC(=O)C1CCCN1C(=O)C(CCCN=C(N)N)NC(=O)C(CC(C)C)NC(=O)C(CC2=CNC3=CC=CC=C32)NC(=O)C(CC4=CC=C(C=C4)O)NC(=O)C(CO)NC(=O)C(CC5=CNC6=CC=CC=C65)NC(=O)C(CC7=CN=CN7)NC(=O)C8CCC(=O)N8 |