For research use only. Not for therapeutic Use.
DDR1-IN-6（Cat No.:I015271）is a potent and selective small-molecule inhibitor of discoidin domain receptor 1 (DDR1), a receptor tyrosine kinase activated by collagen and implicated in cancer progression, fibrosis, and inflammatory diseases. By blocking DDR1 signaling, it disrupts pathways involved in tumor growth, metastasis, extracellular matrix remodeling, and tissue scarring. DDR1-IN-6 is valuable in preclinical research for dissecting DDR1-mediated mechanisms and exploring therapeutic strategies targeting fibrotic and oncogenic disorders. Its selectivity and efficacy make it an important chemical biology tool in drug discovery and disease modeling.
| CAS Number | 2416021-47-9 |
| Synonyms | 7-(2-imidazo[1,2-b]pyridazin-3-ylethynyl)-6-methyl-N-[3-(trifluoromethyl)phenyl]-1,2-benzoxazol-3-amine |
| Molecular Formula | C23H14F3N5O |
| Purity | ≥95% |
| IUPAC Name | 7-(2-imidazo[1,2-b]pyridazin-3-ylethynyl)-6-methyl-N-[3-(trifluoromethyl)phenyl]-1,2-benzoxazol-3-amine |
| InChI | InChI=1S/C23H14F3N5O/c1-14-7-9-19-21(18(14)10-8-17-13-27-20-6-3-11-28-31(17)20)32-30-22(19)29-16-5-2-4-15(12-16)23(24,25)26/h2-7,9,11-13H,1H3,(H,29,30) |
| InChIKey | GDBAAUWGHRTFSE-UHFFFAOYSA-N |
| SMILES | CC1=C(C2=C(C=C1)C(=NO2)NC3=CC=CC(=C3)C(F)(F)F)C#CC4=CN=C5N4N=CC=C5 |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
