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DBCO-Maleimide

DBCO-Maleimide

  • CAT Number: I017225
  • CAS Number: 1395786-30-7
  • Molecular Formula: C₂₅H₂₁N₃O₄
  • Molecular Weight: 427.45
  • Purity: ≥95%
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DBCO-Maleimide (Cat No.:I017225) is a cleavable ADC linker for the synthesis of antibody drug conjugates (ADCs). ADCs are composed of an antibody to which is attached an ADC cytotoxin through an ADC linker. If you need to, please contact us in time, and we will reply to you as soon as possible within 24 hours.

Catalog Number I017225
CAS Number 1395786-30-7
Molecular Formula

C₂₅H₂₁N₃O₄

Purity 95%
Storage -20°C
IUPAC Name N-[3-(2-azatricyclo[10.4.0.04,9]hexadeca-1(16),4,6,8,12,14-hexaen-10-yn-2-yl)-3-oxopropyl]-3-(2,5-dioxopyrrol-1-yl)propanamide
InChI InChI=1S/C25H21N3O4/c29-22(14-16-27-23(30)11-12-24(27)31)26-15-13-25(32)28-17-20-7-2-1-5-18(20)9-10-19-6-3-4-8-21(19)28/h1-8,11-12H,13-17H2,(H,26,29)
InChIKey NHFQNAGPXIVKND-UHFFFAOYSA-N
SMILES C1C2=CC=CC=C2C#CC3=CC=CC=C3N1C(=O)CCNC(=O)CCN4C(=O)C=CC4=O
Reference

[1]. Modified antibody and radioactive metal-labelled antibody. WO2019203191A1.

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